An anagram is a string of letters, which can be rearranged into another word or phrase. For example: orchestra is an anagram of carthorse.
The solution of an anagram is always the name of an NPC. Once the solution is found, the player can get their next clue by talking to that NPC. Often, when talking to an NPC, the player will receive a challenge scroll, puzzle box or light box that they must solve before receiving the next clue.
The anagrams in clue scrolls do not correspond with the number of spaces in a name; an anagram with no spaces may have an answer with a name corresponding with one or more spaces.
Hard Anagrams
| 807 Completable | Anagram | Solution | Location | Challenge answer |
|---|---|---|---|---|
| Baker Climb | Brambickle | Located on Trollweiss Mountain.  You will need to have completed any tier of Combat Diary for the Ghommal's Hilt.
|
Puzzle box | |
| Blue Grim Guided | Lumbridge Guide | Just outside of Lumbridge Castle. | Puzzle box | |
| By Look | Bolkoy | In the Tree Gnome Village general store. | 13 | |
| C On Game Hoc | Gnome Coach | Walking around outside the Gnome Ball course, west of the Grand Tree. | 6 | |
| Copper Ore Crypts | Prospector Percy | You will need someone else or an alt account to clear the rocks. Motherlode Mine, bring a pickaxe on an alt account.
|
12 | |
| Darn Drake | Daer Krand | Upstairs in the eastern wing of the Sisterhood Sanctuary, just north of the The Nightmare's arena. | Puzzle box | |
| Dekagram | Dark mage | Centre of the inner ring of the Abyss. | 13 | |
| Do Say More | Doomsayer | East of Lumbridge Castle, near the Lumbridge Guide. | 95 | |
| Dragons Lament | Strange Old Man | Gravedigger at the Barrows. | 40 | |
| Dr Warden Funk | Drunken Dwarf | In Keldagrim, east side in the house with broken glass. | Puzzle box | |
| Motherboard | Brother Omad | Monastery south of Ardougne. | 129 | |
| My Mangle Lal | Lammy Langle | Hosidius spirit tree patch | Puzzle box | |
| O Birdz A Zany En Pc | Cap'n Izzy no Beard | Entrance of the Brimhaven Agility Arena. | 33 | |
| Quit Horrible Tyrant | Brother Tranquility | Mos Le'Harmless or Harmony Island | 7 | |
| Rat Mat Within | Martin Thwait | Rogues' Den | 2 | |
| Slide Woman | Wise Old Man | Draynor Village | 28 | |
| Veil Veda | Evil Dave | Down the trapdoor in the house directly west of Edgeville bank, where the evil rats are located for the Recipe for Disaster quest.
(Requires completion of Shadow of the Storm quest to open the trapdoor.) (On Examine: A clue suggested by Marfn.) |
666 | |
| Woo An Egg Kiwi | King Awowogei | Must have at least partially completed Monkey Madness I. Located in the building south of the Ape Atoll Teleport. Remember to bring a Karamjan monkey greegree and an M'speak amulet, unless the player has competed Monkey Madness II. Talk to the Elder Guard to gain entrance. | 24 |